After the beginning of autumn, cooler weather, the season when the turn of psoriasis vulgaris is the multi-period. At this point, for patients with psoriasis vulgaris, the correct understanding of psoriasis vulgaris, actively carry out preventive measures, it is very necessary.
Four types of psoriasis vulgaris points
Psoriasis that is commonly known as psoriasis, is a common chronic recurrent skin, and medicine in the motherland, "ringworm", "psoriasis" and other names, according to psoriasis lesions and clinical manifestations of psoriasis can be divided into for the unusual type, type arthropathy, septic cell type, type of psoriasis erythroderma four types of psoriasis. Psoriasis Psoriasis is a fall season high, especially in psoriasis Psoriasis Psoriasis is one of the most common type of psoriasis Psoriasis can be chronic, from local small increase gradually expanded, but also the whole body can be a sudden sharp generalized rash of red spots, the surface of multi-layer silver-white, mostly made in early guttate papules, and more than a small number, about a month or so the body can be generalized. Discoid rash can be expanded into a map-like patch to patch, and some rash hypertrophy, dry, fold split, there are varying degrees of itching. So to remind you that in the Chiu-Liang weather to pay special attention to enhance the immune system can effectively prevent the recurrence of psoriasis vulgaris.
Psoriasis Psoriasis is not infectious
Lesions of psoriasis vulgaris, although the color red, skin thickening, a longer course of disease is a chronic inflammatory skin disease, but the inflammation is not from infectious agents such as bacteria, fungi or parasites, such as a direct result of . Modern medicine has reached a very high level of means testing, but has not been able to prove that psoriasis psoriasis infectious agents. Another observation from clinical practice, there is no transmission of psoriasis vulgaris issues, people close contact between husband and wife is not too much, and, according to the information shows that nearly a thousand追访survey of psoriasis patients with psoriasis was not found transmission between husband and wife cases of psoriasis vulgaris. Fully explained the above psoriasis Psoriasis is not infectious, it is important to understand so that you can lift the psoriasis vulgaris patients, their families and friends of colleagues in this aspect of psoriasis patients with psoriasis to reduce mental stress, in order to patients with psoriasis vulgaris to establish a more relaxed environment of the rehabilitation.
The existence of genetic factors in psoriasis vulgaris
The investigation report at home and abroad with family history of psoriasis pathogenesis of psoriasis patients in about 10% -30%. However, there is no family or psoriasis vulgaris the majority of patients.
Hormone therapy of psoriasis vulgaris to be used with caution
For patients with psoriasis vulgaris, the most chaotic drug use is taboo, especially the hormone-type drugs, the disease is likely to result in delays, and increase. Hormone drugs may cause disease will soon disappear, but once the drug, there will be rebound, and psoriasis vulgaris whose condition had deteriorated, and some are even able to type psoriasis erythroderma. Therefore, to remind patients to the treatment of psoriasis vulgaris to the regular hospital, a doctor by profession according to the patient's condition to be the correct choice of drug treatment.
How to prevent psoriasis vulgaris
First, to avoid infection psoriasis vulgaris
Factor in psoriasis vulgaris infected patients is common predisposing factor, especially for acute psoriasis pathogenesis of psoriasis, and pediatric patients. Factor in infection caused by streptococcal infection pharyngitis, tonsillitis and upper respiratory tract infection the most common. Therefore, in the event of a cold, we must actively treated patients with psoriasis vulgaris in particular, should be the prevention of influenza.
Another kind of infection is wound infection. Trauma is one of the factors that trigger psoriasis. These injuries include burns, scratches, and operations.
Second, to avoid stress psoriasis vulgaris
Mental factors that have become excited or aggravate psoriasis vulgaris primary factor in the disease. Work tension, mental depression, anxiety, excessive grief, family, husband and wife and other factors do not often lead to psychological disorders, subsequently neurological, immune dysfunction, in the genetic background of psoriasis induced psoriasis or psoriasis vulgaris there increase.
Third, psoriasis vulgaris science diet is important
Improper way of life that can not be ignored is also a predisposing factor of psoriasis vulgaris. Food tends to stimulate or aggravate psoriasis psoriasis condition, such as Sim, spicy food, wine, beef and mutton, seafood and so on.
Therefore, the correct choice for patients with psoriasis vulgaris of various types of food is very important, is not conducive to the rehabilitation of food "taboos", is conducive to the rehabilitation of appropriate food choices, the general principles are as follows:
Period to psoriasis vulgaris patients to eat less or eat spicy food irritation, such as chili, pepper, ginger, onions, garlic, etc.; eat less or eat fried food such as deep-fried dough sticks, cake, flavored food; less or do not eat fat, Anabaena complex, such as seafood, beef and mutton, dog, etc..
Psoriasis psoriasis should eat normal vitamin C, vitamin E, vitamin A in food, such as fresh green leafy vegetables, tomatoes, carrots, lean meat, fruits, in order to alleviate the condition of psoriasis and psoriatic lesions of the restoration of .
Fourth, choose the right treatment
The majority of patients with psoriasis vulgaris long history ranging from a few years to several decades, most of them to a lot of local treatment, has spent tens of thousands of dollars of drugs, but when the good and bad condition, recurrent, and time than a serious, from the beginning point of the local papules are gradually developed into a body. Dry skin, scaling, bloodstained, it is painful. Therefore, patients with psoriasis vulgaris to choose professions in hospitals and doctors, and in accordance with medical advice, adherence to treatment, psoriasis
Aug 8, 2009
Psoriasis symptoms
Early green bean for the needles or the size of the red spots rash, gradually expanding, and some points together to form separated from measles each patch. Surface covered with dry silver gently curettage, we can see small blood spots, which is characteristic of the disease.
The majority of skin rashes in patients with clinically manifested as increase in winter and spring and summer and autumn to reduce naturally. Due to the cold climate in winter and spring, dry, skin vasoconstriction, poor blood supply to the skin, the skin caused by loss of custody. Immunodeficiency disorders in individual cases, can lead to disease and thus the temptation is the lack of disease resistance.
The majority of skin rashes in patients with clinically manifested as increase in winter and spring and summer and autumn to reduce naturally. Due to the cold climate in winter and spring, dry, skin vasoconstriction, poor blood supply to the skin, the skin caused by loss of custody. Immunodeficiency disorders in individual cases, can lead to disease and thus the temptation is the lack of disease resistance.
Aug 7, 2009
Psoriasis Research Summary
Chinese and Western medicine in China in 2001 combined meeting of Dermatovenereology, received from all parts of the country papers of the 185 psoriasis, categories, content-rich: A basic theory, experimental studies; dialectical type of Chinese medicine, Chinese medicine treatment mechanism; Chinese and Western medicines , internal external clinical experiences; new therapy, combination therapy for psoriasis and other advanced methods to explore the pathogenesis, reflecting the advanced nature of our academic standards, traditional Chinese and western medicine theory of the continuous deepening of traditional Chinese and western medicine on the treatment of psoriasis a new level.
Special lecture on the psoriasis and the relationship between cytokines. In psoriatic skin lesions: from interleukin-1α (IL1α) increased secretion; tumor necrosis factor-α (INF-α) have increased; IL2 increased; γ together dry Su-(IFN-γ) increased; IL12 increased expression; IL15 and IL15 binding activity were increased; IL10 and its receptor expression. In psoriatic lesions and increased serum IL6; psoriasis lesions鳞屑and suction blister fluid, the granulocyte-macrophage colony-stimulating factor (GM-CSF) increased; psoriatic skin lesions and by IL8 and IL8 body are increased, and does not increase serum IL8. Psoriatic lesions, the epidermal growth factor receptor (EGF) and its ligand TGF-α and increased expression of amphiregulin. Endothelin 1 (ET1) generally do not belong to the family of cytokines, but in structure and function can be considered as a cytokine, in serum and skin lesions of psoriasis in an increase in ET1. However, the incidence of psoriasis is not only concerned with individual cytokines, the role of the main network. Producing cells as a result of keratinocyte (KC) and skin-infiltrating T-cells can be seen as the protagonist of psoriasis, they produce a variety of cytokines will form a special network. In view of the above theory, treatment of psoriasis are: added Th2 or anti-inflammatory cytokines; inhibit or block the pro-inflammatory cytokines, cytokine gene therapy.
Experimental study of the many topics and related cytokines. Based on cytokine secretion patterns, CT4 cells into Th1 and Th2 subsets, Th1 secretion of IL2, INF-γ, etc., that is, Th1-type cytokines; Th2 major secreted IL4, IL6, IL10, etc., in order to TL2-type cytokines. The body to maintain normal Th1/Th2 balance in dynamic network. When the time Th1/Th2 imbalance, which is \ "Th1-Th2 \" drift. Experimental conclusion is that psoriasis is Th1-type response patterns may be the reasoning for the period, in peripheral blood levels of Th1-type cytokine-dominated; stable condition, Th1 cytokine levels, Th2-type cytokine levels. CTLA4Ig was constructed using gene recombination of a soluble chimeric protein, can be reduced Th1 type cytokines, increase of Th2 type cytokines, therefore, can be the treatment of psoriasis CTLA1Ig.
Lesions and peripheral blood in the transforming growth factor (CTGF-β) and receptor expression studies of TGF-β family's role in the pathogenesis, the results suggest that the skin lesions of psoriasis patients or peripheral blood, the existence of TGF-βm RNA expression, so that it can not effectively play the role of negative regulation, resulting in skin lesions or blood, cell proliferation in a transitional state, and dermal endothelial cells can not inhibit the inflammatory cells to the chemotactic effect, and psoriasis pathology change-related. Further on specific targets, such as an in-depth study, the treatment is expected to have a new breakthrough.
Skin lesions of patients with psoriasis vulgaris in keratinocyte growth factor (KGF) and nerve cell growth factor (NGF) in the epidermis of psoriatic keratinocyte proliferation, differentiation has a major role. KGF and its receptor (KGFR) and mainly expressed in basal cells in the grass-roots level; NGF and its receptor expression in the upper epidermis strong, there is weakening and the lower epidermis. Psoriasis patients with the expression of KGF and KGFR significantly increase; In addition, NGF into the outside in the remission period and the location of lesions on the expression of differentiated, suggesting that NGF could be used as an indicator of psoriasis patients.
IL8 and its receptor CXCR2 in psoriatic keratinocytes and the expression of the study results showed that: in patients with skin lesions of psoriasis keratinocytes secrete Department supernatant on neutrophil chemotactic capacity was stronger than the normal control group, the level of IL8 secretion was higher than normal, lesional keratinocytes Department of CXCR2 expression was significantly stronger than the normal control group. Show details www.npx100.com landing. From this description of local skin lesions of patients with psoriasis showed keratinocytes (KC) a high degree of keratinocyte proliferation and secretion of high, high expression of proliferation of the IL8 and its receptor CXCR2. Psoriasis vulgaris in angiogenesis-related factor, vascular endothelial growth factor (VEGF), monocyte chemotactic factor -1 (MCP-1) expression increased, both of which prompted the Senate in the pathogenesis of psoriasis.
Psoriasis calcitonin gene-related peptide secretion and research, results showed that peripheral sensory nerve endings from God peptide CGRP, through receptor-mediated effect on the Langerhans cells in skin lesions under certain conditions to increase its synthesis and secretion of chemokines to promote neutrophil angle in the epidermal layer of aggregation, as well as local inflammatory lymphocytes in the directional migration zone, in order to clarify the abnormal neuroimmunomodulation in the pathogenesis of psoriasis provide a basis. Nitric oxide can cause cultured keratinocytes CGMP increase, CGMP can be caused by increased keratinocyte proliferation; nitric oxide caused keratinocyte chemokine IL8 expression and the psoriatic lesions on the inflammatory cell infiltration. Nitric oxide-type enzyme in the founding of the abnormal expression of the psoriatic lesions, suggesting that nitric oxide and the pathogenesis of psoriasis clearance.
Psoriasis vulgaris in children in the tumor necrosis factor (INF) may be IL6, IL8 increased the main contributing factor, they may be induced or there is some kind of mutual synergies, the joint participation of the immune inflammatory psoriasis pathology process.
Psoriasis with streptococcal throat infection, and skin lesions in the author from the keratin 14 (K14) expression of and with the relationship between streptococcal M6 protein. Conclusions as follows: over-expression of psoriatic epidermal K14, pharyngeal infection with the Streptococcus M6 protein in patients with psoriasis than non-infected with Streptococcus M6 protein, a stronger expression of K14. Another study found that, M6 protein is not a specific area of hemolytic streptococcus pyogenes, if this protein is the trigger factor of psoriasis of the start-up, then with the Streptococcus M6 protein (suppurative streptococcus, Streptococcus agalactiae, it seems Streptococcus) and the incidence of guttate psoriasis have a significant correlation. In β-hemolytic streptococcus-induced model of the pathogenesis of psoriasis, the psoriasis patients to speculate the existence of β-hemolytic streptococcus (SP)-specific lymphocytes, SP as a super-antigen activation of these lymphocytes, after From the release of a large number of cytokines and synergy of these cells so that activation of keratinocyte proliferation, the expression of H-LA-DR, increase Fas antigen, activated T cells and FasL expression in keratinocytes of the Fas antigen-binding surface, induced keratinocyte apoptosis, that is, \ "activation-induced apoptosis in \", which constitutes a psoriasis clinical and pathological features.
Special lecture on the psoriasis and the relationship between cytokines. In psoriatic skin lesions: from interleukin-1α (IL1α) increased secretion; tumor necrosis factor-α (INF-α) have increased; IL2 increased; γ together dry Su-(IFN-γ) increased; IL12 increased expression; IL15 and IL15 binding activity were increased; IL10 and its receptor expression. In psoriatic lesions and increased serum IL6; psoriasis lesions鳞屑and suction blister fluid, the granulocyte-macrophage colony-stimulating factor (GM-CSF) increased; psoriatic skin lesions and by IL8 and IL8 body are increased, and does not increase serum IL8. Psoriatic lesions, the epidermal growth factor receptor (EGF) and its ligand TGF-α and increased expression of amphiregulin. Endothelin 1 (ET1) generally do not belong to the family of cytokines, but in structure and function can be considered as a cytokine, in serum and skin lesions of psoriasis in an increase in ET1. However, the incidence of psoriasis is not only concerned with individual cytokines, the role of the main network. Producing cells as a result of keratinocyte (KC) and skin-infiltrating T-cells can be seen as the protagonist of psoriasis, they produce a variety of cytokines will form a special network. In view of the above theory, treatment of psoriasis are: added Th2 or anti-inflammatory cytokines; inhibit or block the pro-inflammatory cytokines, cytokine gene therapy.
Experimental study of the many topics and related cytokines. Based on cytokine secretion patterns, CT4 cells into Th1 and Th2 subsets, Th1 secretion of IL2, INF-γ, etc., that is, Th1-type cytokines; Th2 major secreted IL4, IL6, IL10, etc., in order to TL2-type cytokines. The body to maintain normal Th1/Th2 balance in dynamic network. When the time Th1/Th2 imbalance, which is \ "Th1-Th2 \" drift. Experimental conclusion is that psoriasis is Th1-type response patterns may be the reasoning for the period, in peripheral blood levels of Th1-type cytokine-dominated; stable condition, Th1 cytokine levels, Th2-type cytokine levels. CTLA4Ig was constructed using gene recombination of a soluble chimeric protein, can be reduced Th1 type cytokines, increase of Th2 type cytokines, therefore, can be the treatment of psoriasis CTLA1Ig.
Lesions and peripheral blood in the transforming growth factor (CTGF-β) and receptor expression studies of TGF-β family's role in the pathogenesis, the results suggest that the skin lesions of psoriasis patients or peripheral blood, the existence of TGF-βm RNA expression, so that it can not effectively play the role of negative regulation, resulting in skin lesions or blood, cell proliferation in a transitional state, and dermal endothelial cells can not inhibit the inflammatory cells to the chemotactic effect, and psoriasis pathology change-related. Further on specific targets, such as an in-depth study, the treatment is expected to have a new breakthrough.
Skin lesions of patients with psoriasis vulgaris in keratinocyte growth factor (KGF) and nerve cell growth factor (NGF) in the epidermis of psoriatic keratinocyte proliferation, differentiation has a major role. KGF and its receptor (KGFR) and mainly expressed in basal cells in the grass-roots level; NGF and its receptor expression in the upper epidermis strong, there is weakening and the lower epidermis. Psoriasis patients with the expression of KGF and KGFR significantly increase; In addition, NGF into the outside in the remission period and the location of lesions on the expression of differentiated, suggesting that NGF could be used as an indicator of psoriasis patients.
IL8 and its receptor CXCR2 in psoriatic keratinocytes and the expression of the study results showed that: in patients with skin lesions of psoriasis keratinocytes secrete Department supernatant on neutrophil chemotactic capacity was stronger than the normal control group, the level of IL8 secretion was higher than normal, lesional keratinocytes Department of CXCR2 expression was significantly stronger than the normal control group. Show details www.npx100.com landing. From this description of local skin lesions of patients with psoriasis showed keratinocytes (KC) a high degree of keratinocyte proliferation and secretion of high, high expression of proliferation of the IL8 and its receptor CXCR2. Psoriasis vulgaris in angiogenesis-related factor, vascular endothelial growth factor (VEGF), monocyte chemotactic factor -1 (MCP-1) expression increased, both of which prompted the Senate in the pathogenesis of psoriasis.
Psoriasis calcitonin gene-related peptide secretion and research, results showed that peripheral sensory nerve endings from God peptide CGRP, through receptor-mediated effect on the Langerhans cells in skin lesions under certain conditions to increase its synthesis and secretion of chemokines to promote neutrophil angle in the epidermal layer of aggregation, as well as local inflammatory lymphocytes in the directional migration zone, in order to clarify the abnormal neuroimmunomodulation in the pathogenesis of psoriasis provide a basis. Nitric oxide can cause cultured keratinocytes CGMP increase, CGMP can be caused by increased keratinocyte proliferation; nitric oxide caused keratinocyte chemokine IL8 expression and the psoriatic lesions on the inflammatory cell infiltration. Nitric oxide-type enzyme in the founding of the abnormal expression of the psoriatic lesions, suggesting that nitric oxide and the pathogenesis of psoriasis clearance.
Psoriasis vulgaris in children in the tumor necrosis factor (INF) may be IL6, IL8 increased the main contributing factor, they may be induced or there is some kind of mutual synergies, the joint participation of the immune inflammatory psoriasis pathology process.
Psoriasis with streptococcal throat infection, and skin lesions in the author from the keratin 14 (K14) expression of and with the relationship between streptococcal M6 protein. Conclusions as follows: over-expression of psoriatic epidermal K14, pharyngeal infection with the Streptococcus M6 protein in patients with psoriasis than non-infected with Streptococcus M6 protein, a stronger expression of K14. Another study found that, M6 protein is not a specific area of hemolytic streptococcus pyogenes, if this protein is the trigger factor of psoriasis of the start-up, then with the Streptococcus M6 protein (suppurative streptococcus, Streptococcus agalactiae, it seems Streptococcus) and the incidence of guttate psoriasis have a significant correlation. In β-hemolytic streptococcus-induced model of the pathogenesis of psoriasis, the psoriasis patients to speculate the existence of β-hemolytic streptococcus (SP)-specific lymphocytes, SP as a super-antigen activation of these lymphocytes, after From the release of a large number of cytokines and synergy of these cells so that activation of keratinocyte proliferation, the expression of H-LA-DR, increase Fas antigen, activated T cells and FasL expression in keratinocytes of the Fas antigen-binding surface, induced keratinocyte apoptosis, that is, \ "activation-induced apoptosis in \", which constitutes a psoriasis clinical and pathological features.
Psoriasis treatment common summary
Psoriasis is a very stubborn chronic inflammatory skin disease, many patients with the treatment of psoriasis unknown reason, seek medical treatment for several decades has been hard to see the effect of body and mind have been a great blow, and even lost to confidence in treatment, where we introduce the system for all common treatment of psoriasis:
A treatment of psoriasis: physical therapy
There are ultraviolet therapy, photochemical therapy, hyperbaric oxygen law, medicine bath therapy and acupuncture points, such as embedding.
Second, the treatment of psoriasis: topical therapy
1 horny reducing agent, skin exfoliation agent,
2 anti-inflammatory agents: there are commonly used chlorine-fold Mimatsu acid ointment, clobetasol propionate ointment, hydrocortisone ointment Lambda ointment triamcinolone, triamcinolone ointment, skin diseases, such as Ning Tiegao.
3 cell agents: such as - fluorouracil gel or cream, cream methotrexate, camptothecin DMSO solution, cream hydroxyurea, carmustine tincture, ointment, such as mustard gas.
Third, the treatment of psoriasis: The use of therapy
1. Antibiotics or antimicrobial therapy
2. Cyclosporin therapy
3. Victoria A acid therapy
4. Vitamin therapy
5. Stromal steroid hormone therapy
6. Chinese medicine category
Among them, the formal adoption of the scientific Chinese medicine treatment of psoriasis is the most popular and clinical effects of the best way to heal.
In short, the treatment of psoriasis, only the overall focus, integrated treatment, in order to achieve the best therapeutic effect. Subjective, the patient with attention to the common cause of symptomatic treatment and application, systemic treatment and local treatment, short-term efficacy and long-term efficacy of drug treatment and psychotherapy, as well as between treatment and prevention combination. In the objective context, it should be a comprehensive treatment of absorption in the Western point of view of the excellent two long, using a combination of Chinese and Western medicine therapy, in particular, the current source to the treatment of Western medicine and Chinese medicine gene internal conditioning treatment that combines "immune gene therapy of Chinese medicine", because significant effect, but the majority of psoriasis patients are welcomed and praised.
A treatment of psoriasis: physical therapy
There are ultraviolet therapy, photochemical therapy, hyperbaric oxygen law, medicine bath therapy and acupuncture points, such as embedding.
Second, the treatment of psoriasis: topical therapy
1 horny reducing agent, skin exfoliation agent,
2 anti-inflammatory agents: there are commonly used chlorine-fold Mimatsu acid ointment, clobetasol propionate ointment, hydrocortisone ointment Lambda ointment triamcinolone, triamcinolone ointment, skin diseases, such as Ning Tiegao.
3 cell agents: such as - fluorouracil gel or cream, cream methotrexate, camptothecin DMSO solution, cream hydroxyurea, carmustine tincture, ointment, such as mustard gas.
Third, the treatment of psoriasis: The use of therapy
1. Antibiotics or antimicrobial therapy
2. Cyclosporin therapy
3. Victoria A acid therapy
4. Vitamin therapy
5. Stromal steroid hormone therapy
6. Chinese medicine category
Among them, the formal adoption of the scientific Chinese medicine treatment of psoriasis is the most popular and clinical effects of the best way to heal.
In short, the treatment of psoriasis, only the overall focus, integrated treatment, in order to achieve the best therapeutic effect. Subjective, the patient with attention to the common cause of symptomatic treatment and application, systemic treatment and local treatment, short-term efficacy and long-term efficacy of drug treatment and psychotherapy, as well as between treatment and prevention combination. In the objective context, it should be a comprehensive treatment of absorption in the Western point of view of the excellent two long, using a combination of Chinese and Western medicine therapy, in particular, the current source to the treatment of Western medicine and Chinese medicine gene internal conditioning treatment that combines "immune gene therapy of Chinese medicine", because significant effect, but the majority of psoriasis patients are welcomed and praised.
Psoriasis medication guide
Different phases, different formulations of the same drugs have different formulations, such as solution, paste, powder, lotion, ointment, tincture, such as emulsion and. Different forms, have different functions and indications, it should be based on different stages of skin symptoms and lesions characteristic of the correct choice of different formulations. Local general acute phase have swelling, blisters, erosion, the wet multi-choice solution, could play a role in anti-inflammatory; are fluid, the first wet with solution, followed by oil. Lesions in the subacute period, reduce swelling, exudate reduction can be selected, as appropriate, paste, powder and lotion, in order to play its anti-inflammatory, antipruritic, convergence, the protective effect. Thickening of the skin lesions in chronic phase, showed lichenoid changes, the use of ointment and cream, and they penetrate the strong, lasting role, and the role of lubrication and skin care. It should also be noted: Even if the same drug, same dosage form can also be due to differences in the role of different concentrations. Such as: 3% salicylic acid with the role of disinfection and sterilization, and 10% salicylic acid have a role in skin softening and dissolving, 20% of salicylic acid is a corrosive.
Symptomatic medication, drug selection, such as accurate risk dermatitis, eczema等症with ringworm medicine涂搽will inflammation, lesions increase; and the skin disease ringworm ointment treatment with hormones, just like adding fuel to the fire, will lead to the breeding of bacteria , exacerbations; originally drug eruption caused by sulfa drugs, sulfadiazine If wet, it is even more worse. Some drugs, such as realgar cream, sulfur cream一字之差only, and uses different, the former for psoriasis (psoriasis), the latter used for scabies, acne, eczema and so on, must not be confused. The drug also does not deserve its name, such as the cortex hormones triamcinolone cream, and can not be used with "inflammatory" nature of the infectious skin diseases, such as fungal infections, viral infections and skin diseases such as tuberculosis should be classified as taboo. Only chicken pox as an example, chickenpox is not in itself cause serious harm, if the abuse or triamcinolone ointment肤轻松may occur hemorrhagic chickenpox or secondary bacterial infections of the severe adverse consequences. Therefore, when suffering from skin diseases, doctors should be a clear diagnosis and prescription for proper use.
Master the use of the scientific use of time and frequency of drug skin also pay attention to. Medicine and lotion, easy to reduce the effect of evaporation, relative to the number of drug use more generally for every three hours apply 1; tincture, ointment lasting effect, sooner or later each day can be used 1. Wet methods should be appropriate, before treatment, in addition to cleaning outside the affected area, the skin callus should be sterilized and softened after oil拭去food. Department if the lesion diameter greater than 0.5 centimeters see the blisters, it is necessary to disinfect air in order to extract the contents of syringes, blister wall retained. Use of the site of hair before剃去hair, and then on the drug.
The person should be, strictly taboo selected drugs to be taken into consideration age, gender, disease location and physical factors such as patients. Such as the young and old patients with low concentrations of drugs should be elected; maternal drug use outside, we should take into account the drugs on the fetus, the impact of乳儿; face, breasts, vulva Department is not available or irritant at high concentrations and strong tincture of the drug, children, women should be used with caution; the palm of your hand, foot, etc. available at the bottom of high concentrations of drug. Sensitive skin, use a low concentration, followed by a high concentration. Easily sensitized to the drug or drugs, first used a small area, such as non-response, and then a gradual increase in the basis of need and expanding the use of an area of concentration. In addition, when the skin but also to observe the drug, if erythema or eczema-like rash, itching and there is, headache and other allergic reactions, they should stop immediately and go to the hospital diagnosis and treatment of
Symptomatic medication, drug selection, such as accurate risk dermatitis, eczema等症with ringworm medicine涂搽will inflammation, lesions increase; and the skin disease ringworm ointment treatment with hormones, just like adding fuel to the fire, will lead to the breeding of bacteria , exacerbations; originally drug eruption caused by sulfa drugs, sulfadiazine If wet, it is even more worse. Some drugs, such as realgar cream, sulfur cream一字之差only, and uses different, the former for psoriasis (psoriasis), the latter used for scabies, acne, eczema and so on, must not be confused. The drug also does not deserve its name, such as the cortex hormones triamcinolone cream, and can not be used with "inflammatory" nature of the infectious skin diseases, such as fungal infections, viral infections and skin diseases such as tuberculosis should be classified as taboo. Only chicken pox as an example, chickenpox is not in itself cause serious harm, if the abuse or triamcinolone ointment肤轻松may occur hemorrhagic chickenpox or secondary bacterial infections of the severe adverse consequences. Therefore, when suffering from skin diseases, doctors should be a clear diagnosis and prescription for proper use.
Master the use of the scientific use of time and frequency of drug skin also pay attention to. Medicine and lotion, easy to reduce the effect of evaporation, relative to the number of drug use more generally for every three hours apply 1; tincture, ointment lasting effect, sooner or later each day can be used 1. Wet methods should be appropriate, before treatment, in addition to cleaning outside the affected area, the skin callus should be sterilized and softened after oil拭去food. Department if the lesion diameter greater than 0.5 centimeters see the blisters, it is necessary to disinfect air in order to extract the contents of syringes, blister wall retained. Use of the site of hair before剃去hair, and then on the drug.
The person should be, strictly taboo selected drugs to be taken into consideration age, gender, disease location and physical factors such as patients. Such as the young and old patients with low concentrations of drugs should be elected; maternal drug use outside, we should take into account the drugs on the fetus, the impact of乳儿; face, breasts, vulva Department is not available or irritant at high concentrations and strong tincture of the drug, children, women should be used with caution; the palm of your hand, foot, etc. available at the bottom of high concentrations of drug. Sensitive skin, use a low concentration, followed by a high concentration. Easily sensitized to the drug or drugs, first used a small area, such as non-response, and then a gradual increase in the basis of need and expanding the use of an area of concentration. In addition, when the skin but also to observe the drug, if erythema or eczema-like rash, itching and there is, headache and other allergic reactions, they should stop immediately and go to the hospital diagnosis and treatment of
Aug 5, 2009
"Psoriasis" is not ringworm
Because the whole body are often different sizes, and stubbornly intractable condition, it commonly known as "psoriasis." Many people mistakenly believe that its a disease dermatophytes away with the treatment of ringworm medicine. In fact, psoriasis is not ringworm, but a multi-gene genetic disease. Modern medicine for ringworm of the name refers to superficial skin disease caused by fungi, such as the hands of ringworm, tinea pedis, tinea corporis, tinea corporis, tinea versicolor, etc.. Since psoriasis is not ringworm, then, why some people with some medicine for the treatment of ringworm it effective? This is because the drug treatment of ringworm usually contain salicylic acid, and salicylic acid not only the role of anti-fungal, as well as the role of keratinocyte dissociation and anti-inflammatory effect, it can be used for the treatment of psoriasis, so patients with reduced鳞屑condition improved.
The incidence of psoriasis is relatively complex, the current medical has confirmed the existence of psoriasis in patients with hereditary defects, or the existence of susceptibility genes, together with a number of environmental factors (as respiratory tract infection, trauma, trauma, etc.), lead to the performance of patients with immune abnormalities, which cause the occurrence of psoriasis. In other words, the prevalence of psoriasis tend to have family members, and future generations of high incidence. However, we should not mistake their own and therefore can not cure psoriasis, or mistakenly believe that future generations will be incidence of family or origin. This is because:
1. Genetic illness is only a certain tendency, if the attention of prevention, it is possible to non-disease.
2. Environmental factors is an important factor in the incidence, so we know what environmental factors can induce the occurrence of psoriasis, leading to early prevention and control of it, is to avoid suffering from psoriasis.
So, what are the factors that induced psoriasis is a major factor in this:
1. Seasonal factors: the majority of patients with psoriasis in autumn and winter and heavier easy to relapse during the summer to ease or subside naturally. This may be related to climate, temperature, humidity and sunlight number of time-related. Long summer of sunshine, outdoor activities, people and more parts of the skin by ultraviolet radiation exposure time, and summer high temperatures, sweating in patients with psoriasis, and the number of multi-bath, bathing frequency and more beneficial to the skin lesions clean and the regression . On the contrary, during the winter, the short duration of bright sunshine, low temperatures, outdoor activities, fewer patients with less sweat, bathing less detrimental to the skin lesions clean and the dissipated. Therefore, autumn and winter the majority of patients with psoriasis recurrence and to increase easy.
2. The spirit of factors: skin doctors have noted that some mental events can lead to psychological stress and psoriasis to aggravate their condition. Psychological stress of these events, including stress, emotional suppression and death of a spouse or family, work smoothly, and economic difficulties. 1114 cases have been reported in patients with psoriasis, 40% occurred in patients with psoriasis in the concerns, which concerns 37% of patients with exacerbations.
3. Drug factors: number of drug-induced psoriasis or aggravate their condition, such as the β blocker propranolol, chloride Quinoline anti-malarial drugs, non-steroidal anti-inflammatory drug indomethacin, IL-- Ⅱ, γ - interferon, lithium, etc., these drugs can be in the treatment of other diseases, the trigger psoriasis or aggravate their condition. Therefore, psoriasis patients, regardless of their severity or whether it has been cured, should avoid the use of these drugs.
At present, the clinical cure of psoriasis is not difficult, mainly to prevent its recurrence. Patients mainly in their daily lives should pay attention to the following five points:
1. To maintain optimism and avoid mental tension, the lifting of ideological concerns, do "not only to them, security is" a correct view of the arrival of the disease.
2. Daily life, should enhance the physical, to enhance the body's immune system, pay attention to the prevention of colds, tonsillitis, etc., as bacterial or viral infection tends to aggravate or induce psoriasis.
3. Food should be the law of life, try to quit drinking less, pay attention to nutrition, adequate protein and not partial eclipse, a moderate diet. To keep the skin clean, bathe regularly, do not hot wash.
4. In advanced disease, regular hospital to receive regular treatment, not to abuse drugs, do not blindly use of drugs, do not aggravate their condition may make use of the drug.
5. If the incidence of re-performance summer winter light, strong seasonal and should be in the incidence of the season before, under the guidance of a doctor for preventive treatment.
To achieve the above, the condition can be long-term remission or even cured.
The incidence of psoriasis is relatively complex, the current medical has confirmed the existence of psoriasis in patients with hereditary defects, or the existence of susceptibility genes, together with a number of environmental factors (as respiratory tract infection, trauma, trauma, etc.), lead to the performance of patients with immune abnormalities, which cause the occurrence of psoriasis. In other words, the prevalence of psoriasis tend to have family members, and future generations of high incidence. However, we should not mistake their own and therefore can not cure psoriasis, or mistakenly believe that future generations will be incidence of family or origin. This is because:
1. Genetic illness is only a certain tendency, if the attention of prevention, it is possible to non-disease.
2. Environmental factors is an important factor in the incidence, so we know what environmental factors can induce the occurrence of psoriasis, leading to early prevention and control of it, is to avoid suffering from psoriasis.
So, what are the factors that induced psoriasis is a major factor in this:
1. Seasonal factors: the majority of patients with psoriasis in autumn and winter and heavier easy to relapse during the summer to ease or subside naturally. This may be related to climate, temperature, humidity and sunlight number of time-related. Long summer of sunshine, outdoor activities, people and more parts of the skin by ultraviolet radiation exposure time, and summer high temperatures, sweating in patients with psoriasis, and the number of multi-bath, bathing frequency and more beneficial to the skin lesions clean and the regression . On the contrary, during the winter, the short duration of bright sunshine, low temperatures, outdoor activities, fewer patients with less sweat, bathing less detrimental to the skin lesions clean and the dissipated. Therefore, autumn and winter the majority of patients with psoriasis recurrence and to increase easy.
2. The spirit of factors: skin doctors have noted that some mental events can lead to psychological stress and psoriasis to aggravate their condition. Psychological stress of these events, including stress, emotional suppression and death of a spouse or family, work smoothly, and economic difficulties. 1114 cases have been reported in patients with psoriasis, 40% occurred in patients with psoriasis in the concerns, which concerns 37% of patients with exacerbations.
3. Drug factors: number of drug-induced psoriasis or aggravate their condition, such as the β blocker propranolol, chloride Quinoline anti-malarial drugs, non-steroidal anti-inflammatory drug indomethacin, IL-- Ⅱ, γ - interferon, lithium, etc., these drugs can be in the treatment of other diseases, the trigger psoriasis or aggravate their condition. Therefore, psoriasis patients, regardless of their severity or whether it has been cured, should avoid the use of these drugs.
At present, the clinical cure of psoriasis is not difficult, mainly to prevent its recurrence. Patients mainly in their daily lives should pay attention to the following five points:
1. To maintain optimism and avoid mental tension, the lifting of ideological concerns, do "not only to them, security is" a correct view of the arrival of the disease.
2. Daily life, should enhance the physical, to enhance the body's immune system, pay attention to the prevention of colds, tonsillitis, etc., as bacterial or viral infection tends to aggravate or induce psoriasis.
3. Food should be the law of life, try to quit drinking less, pay attention to nutrition, adequate protein and not partial eclipse, a moderate diet. To keep the skin clean, bathe regularly, do not hot wash.
4. In advanced disease, regular hospital to receive regular treatment, not to abuse drugs, do not blindly use of drugs, do not aggravate their condition may make use of the drug.
5. If the incidence of re-performance summer winter light, strong seasonal and should be in the incidence of the season before, under the guidance of a doctor for preventive treatment.
To achieve the above, the condition can be long-term remission or even cured.
My experience in the treatment of psoriasis!
Is well known that psoriasis is relatively refractory intractable skin diseases, skin diseases, I engaged in clinical work for eight years, has treated many patients with psoriasis, the result is not satisfactory, although the response of many patients, However, many patients with slowly receding, but also easy to relapse! Recently, because of Dermatology in our hospital in patients with psoriasis are more to them through treatment, I found a better method of treatment, most patients before treatment compared very well sum up the experience for everyone.
For general treatment in three steps:
1. Chinese medicine Oral:
Under the condition of the different stages of development, physical and disease in patients with the severity of the decoction of Chinese medicine to take oral treatment, can quickly control the disease progresses, the lesions subsided to promote! Recommends against the use of proprietary Chinese medicines (such as compound Qingdai) or Western (Diyin Tablet, Capsule Viaminati even neopterin methylamine, etc.). Chinese medicine treatment is divided into two types: hot-Yun blood poisoning (advanced) and blood type impatient wind Sheng (quiescent). Based on combination of different types of physical and tongue in patients with vein, take a different prescriptions, blood type heat Yun drugs mainly Sophorae Health,, habitat, Shikonin, Chishao, Salvia, Millettia, forsythia, Dragon, two flowers; blood type impatient wind sung mainly Angelica, Asparagus, Ophiopogon japonicus, root, red sage root, Smilax glabra, fresh white skin, gill Tribulus terrestris, vespae mainly clinical addition and subtraction.
II. Phototherapy
Narrow-band uvb light therapy, according to patient's skin type, minimal erythema to determine the amount of time the next day, gradually increasing the energy. Began to increase faster, slower increase of the late energy. Does not exceed the maximum 1.5j! Use of the night before, it is best to use clean coal tar lotion rash parts, light treatment and before the wash!
III. External use drugs:
Thicker parts of the scalp skin using appropriate spray this may be, well, irritating small, quick effect! Thicker parts of the trunk rash of wrestlers can use the ointment!
In addition, the course of treatment, the patient's diet is more important personal habits, eating light, spicy deprivation and strict忌酒!涂擦Vaseline dry skin are advised to maintain skin moisture. Avoid feeling irritable! To achieve the above, the treatment of psoriasis is not difficult on the!
For general treatment in three steps:
1. Chinese medicine Oral:
Under the condition of the different stages of development, physical and disease in patients with the severity of the decoction of Chinese medicine to take oral treatment, can quickly control the disease progresses, the lesions subsided to promote! Recommends against the use of proprietary Chinese medicines (such as compound Qingdai) or Western (Diyin Tablet, Capsule Viaminati even neopterin methylamine, etc.). Chinese medicine treatment is divided into two types: hot-Yun blood poisoning (advanced) and blood type impatient wind Sheng (quiescent). Based on combination of different types of physical and tongue in patients with vein, take a different prescriptions, blood type heat Yun drugs mainly Sophorae Health,, habitat, Shikonin, Chishao, Salvia, Millettia, forsythia, Dragon, two flowers; blood type impatient wind sung mainly Angelica, Asparagus, Ophiopogon japonicus, root, red sage root, Smilax glabra, fresh white skin, gill Tribulus terrestris, vespae mainly clinical addition and subtraction.
II. Phototherapy
Narrow-band uvb light therapy, according to patient's skin type, minimal erythema to determine the amount of time the next day, gradually increasing the energy. Began to increase faster, slower increase of the late energy. Does not exceed the maximum 1.5j! Use of the night before, it is best to use clean coal tar lotion rash parts, light treatment and before the wash!
III. External use drugs:
Thicker parts of the scalp skin using appropriate spray this may be, well, irritating small, quick effect! Thicker parts of the trunk rash of wrestlers can use the ointment!
In addition, the course of treatment, the patient's diet is more important personal habits, eating light, spicy deprivation and strict忌酒!涂擦Vaseline dry skin are advised to maintain skin moisture. Avoid feeling irritable! To achieve the above, the treatment of psoriasis is not difficult on the!
What is it psoriasis?
Psoriasis, because the whole body are often different sizes, and stubbornly intractable condition, it commonly known as "psoriasis." Many people mistakenly believe that its a disease dermatophytes away with the treatment of ringworm medicine. In fact, psoriasis is not ringworm, but a multi-gene genetic disease. Modern medicine for ringworm of the name refers to superficial skin disease caused by fungi, such as the hands of ringworm, tinea pedis, tinea corporis, tinea corporis, tinea versicolor, etc.. Since psoriasis is not ringworm, then, why some people with some medicine for the treatment of ringworm it effective? This is because the drug treatment of ringworm usually contain salicylic acid, and salicylic acid not only the role of anti-fungal, as well as the role of keratinocyte dissociation and anti-inflammatory effect, it can be used for the treatment of psoriasis, so patients with reduced condition improved.
The incidence of psoriasis is relatively complex, the current medical has confirmed the existence of psoriasis in patients with hereditary defects, or the existence of susceptibility genes, together with a number of environmental factors (as respiratory tract infection, trauma, trauma, etc.), lead to the performance of patients with immune abnormalities, which cause the occurrence of psoriasis. In other words, the prevalence of psoriasis tend to have family members, and future generations of high incidence. However, we should not mistake their own and therefore can not cure psoriasis, or mistakenly believe that future generations will be incidence of family or origin. This is because:
1. Genetic illness is only a certain tendency, if the attention of prevention, it is possible to non-disease.
2. Environmental factors is an important factor in the incidence, so we know what environmental factors can induce the occurrence of psoriasis, leading to early prevention and control of it, is to avoid suffering from psoriasis.
So, what are the factors that induced psoriasis is a major factor in this:
1. Seasonal factors: the majority of patients with psoriasis in autumn and winter and heavier easy to relapse during the summer to ease or subside naturally. This may be related to climate, temperature, humidity and sunlight number of time-related. Long summer of sunshine, outdoor activities, people and more parts of the skin by ultraviolet radiation exposure time, and summer high temperatures, sweating in patients with psoriasis, and the number of multi-bath, bathing frequency and more beneficial to the skin lesions clean and the regression . On the contrary, during the winter, the short duration of bright sunshine, low temperatures, outdoor activities, fewer patients with less sweat, bathing less detrimental to the skin lesions clean and the dissipated. Therefore, autumn and winter the majority of patients with psoriasis recurrence and to increase easy.
2. The spirit of factors: skin doctors have noted that some mental events can lead to psychological stress and psoriasis to aggravate their condition. Psychological stress of these events, including stress, emotional suppression and death of a spouse or family, work smoothly, and economic difficulties. 1114 cases have been reported in patients with psoriasis, 40% occurred in patients with psoriasis in the concerns, which concerns 37% of patients with exacerbations.
3. Drug factors: number of drug-induced psoriasis or aggravate their condition, such as the β blocker propranolol, chloride Quinoline anti-malarial drugs, non-steroidal anti-inflammatory drug indomethacin, IL-- Ⅱ, γ - interferon, lithium, etc., these drugs can be in the treatment of other diseases, the trigger psoriasis or aggravate their condition. Therefore, psoriasis patients, regardless of their severity or whether it has been cured, should avoid the use of these drugs.
At present, the clinical cure of psoriasis is not difficult, mainly to prevent its recurrence. Patients mainly in their daily lives should pay attention to the following five points:
1. To maintain optimism and avoid mental tension, the lifting of ideological concerns, do "not only to them, security is" a correct view of the arrival of the disease.
2. Daily life, should enhance the physical, to enhance the body's immune system, pay attention to the prevention of colds, tonsillitis, etc., as bacterial or viral infection tends to aggravate or induce psoriasis.
3. Food should be the law of life, try to quit drinking less, pay attention to nutrition, adequate protein and not partial eclipse, a moderate diet. To keep the skin clean, bathe regularly, do not hot wash.
4. In advanced disease, regular hospital to receive regular treatment, not to abuse drugs, do not blindly use of drugs, do not aggravate their condition may make use of the drug.
5. If the incidence of re-performance summer winter light, strong seasonal and should be in the incidence of the season before, under the guidance of a doctor for preventive treatment.
To achieve the above, the condition can be long-term remission or even cured.
The incidence of psoriasis is relatively complex, the current medical has confirmed the existence of psoriasis in patients with hereditary defects, or the existence of susceptibility genes, together with a number of environmental factors (as respiratory tract infection, trauma, trauma, etc.), lead to the performance of patients with immune abnormalities, which cause the occurrence of psoriasis. In other words, the prevalence of psoriasis tend to have family members, and future generations of high incidence. However, we should not mistake their own and therefore can not cure psoriasis, or mistakenly believe that future generations will be incidence of family or origin. This is because:
1. Genetic illness is only a certain tendency, if the attention of prevention, it is possible to non-disease.
2. Environmental factors is an important factor in the incidence, so we know what environmental factors can induce the occurrence of psoriasis, leading to early prevention and control of it, is to avoid suffering from psoriasis.
So, what are the factors that induced psoriasis is a major factor in this:
1. Seasonal factors: the majority of patients with psoriasis in autumn and winter and heavier easy to relapse during the summer to ease or subside naturally. This may be related to climate, temperature, humidity and sunlight number of time-related. Long summer of sunshine, outdoor activities, people and more parts of the skin by ultraviolet radiation exposure time, and summer high temperatures, sweating in patients with psoriasis, and the number of multi-bath, bathing frequency and more beneficial to the skin lesions clean and the regression . On the contrary, during the winter, the short duration of bright sunshine, low temperatures, outdoor activities, fewer patients with less sweat, bathing less detrimental to the skin lesions clean and the dissipated. Therefore, autumn and winter the majority of patients with psoriasis recurrence and to increase easy.
2. The spirit of factors: skin doctors have noted that some mental events can lead to psychological stress and psoriasis to aggravate their condition. Psychological stress of these events, including stress, emotional suppression and death of a spouse or family, work smoothly, and economic difficulties. 1114 cases have been reported in patients with psoriasis, 40% occurred in patients with psoriasis in the concerns, which concerns 37% of patients with exacerbations.
3. Drug factors: number of drug-induced psoriasis or aggravate their condition, such as the β blocker propranolol, chloride Quinoline anti-malarial drugs, non-steroidal anti-inflammatory drug indomethacin, IL-- Ⅱ, γ - interferon, lithium, etc., these drugs can be in the treatment of other diseases, the trigger psoriasis or aggravate their condition. Therefore, psoriasis patients, regardless of their severity or whether it has been cured, should avoid the use of these drugs.
At present, the clinical cure of psoriasis is not difficult, mainly to prevent its recurrence. Patients mainly in their daily lives should pay attention to the following five points:
1. To maintain optimism and avoid mental tension, the lifting of ideological concerns, do "not only to them, security is" a correct view of the arrival of the disease.
2. Daily life, should enhance the physical, to enhance the body's immune system, pay attention to the prevention of colds, tonsillitis, etc., as bacterial or viral infection tends to aggravate or induce psoriasis.
3. Food should be the law of life, try to quit drinking less, pay attention to nutrition, adequate protein and not partial eclipse, a moderate diet. To keep the skin clean, bathe regularly, do not hot wash.
4. In advanced disease, regular hospital to receive regular treatment, not to abuse drugs, do not blindly use of drugs, do not aggravate their condition may make use of the drug.
5. If the incidence of re-performance summer winter light, strong seasonal and should be in the incidence of the season before, under the guidance of a doctor for preventive treatment.
To achieve the above, the condition can be long-term remission or even cured.
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